Hôpital Paris Saint-Joseph

Paracetamol: A History of Assumptions, Errors, and Evidence Reversals in Pain Management

Abstract Purpose of Review Paracetamol (acetaminophen) is among the most widely used medications in the history of humanity for treatment of pain conditions. For more than half a century, it has occupied a unique position as the archetypal first-line analgesic and antipyretic, re...

Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoids

BACKGROUND: Lung neuroendocrine tumours (NETs, also known as carcinoids) are rapidly rising in incidence worldwide but have unknown aetiology and limited therapeutic options beyond surgery. The current WHO classification, based on mitotic count and presence or absence of necrosis...