Hôpital Antoine-Béclère

Efficacy and safety of temporary selective portal vein embolization before major hepatectomy (EMBORES): a phase 2 trial

Background Portal vein embolization (PVE) is routinely used before major hepatectomy to induce hypertrophy of the future liver remnant (FLR) and reduce post-hepatectomy liver failure. Conventional PVE relies on permanent embolic agents, resulting in irreversible portal occlusion,...

The robotic PIANO: a critical narrative review of surgeon-controlled operative polyphony, human factors, and robotic training

Abstract Robotic surgery can concentrate control of several technical functions at the console, but such concentration does not itself confer clinical independence, reduce dependence on the perioperative team, or improve patient outcomes. We define surgeon-controlled operative po...

Estrogen Receptor Beta Isoforms Interplay Integrates Nuclear and Extra‐Nuclear Signaling to Modulate Human Granulosa Cell Growth

Estradiol (E2) regulates ovarian follicular development and granulosa cell (GC) function primarily through estrogen receptor β (ERβ). Human GCs express several ERβ isoforms, including ERβ1, ERβ2, ERβ4, and ERβ5, but how their relative abundance modulates estrogen signaling remain...

Mild stimulated cycles with timed intercourse in women with idiopathic infertility and decreased ovarian reserve: can it be a therapeutic option before oocyte donation?

Woman natural fertility declines physiologically with age, driven by accelerated follicular depletion and subtle ovulatory dysfunctions. As age at first pregnancy increases, women with decreased ovarian reserve (DOR) represent a growing proportion of those seeking assisted reprod...