Hôpital Ambroise-Paré

Assessment of blinding in pharmacotherapy and noninvasive neuromodulation randomized controlled trials for neuropathic pain in adults

In randomized controlled trials (RCTs), study participants and research personnel are often blinded to minimize biases related to knowing treatment allocation. To determine if blinding was effective, participants may be asked which treatment they believe they received (“treatment...

Contact injury mechanism is independently associated with greater Anterior Cruciate Ligament Injury Severity Scale severity in patients undergoing primary anterior cruciate ligament reconstruction

Abstract Purpose To determine whether injury mechanism and sport category were independently associated with overall structural injury severity after sport‐related primary anterior cruciate ligament (ACL) rupture, as quantified by the Anterior Cruciate Ligament Injury Severity Sc...

Paraneoplastic Autoimmune Multiorgan Syndrome: Diagnostic Lessons for Pediatricians

We report the challenging diagnosis of an 11-year-old boy, presenting with subacute erythroblastopenia, followed by a multisystemic immune-mediated syndrome characterized by polymorphic mucocutaneous manifestations, associated with severe myositis related to a dermatomyositis-lik...

Long‐term survivorship of medial meniscus posterior horn repair during revision anterior cruciate ligament reconstruction: 10‐year results from the SANTI Group

Abstract Purpose To evaluate the long‐term rate of secondary medial meniscectomy following medial meniscus posterior horn repair performed during revision anterior cruciate ligament reconstruction (ACLR) and to compare contemporary posteromedial suture‐hook repair with other repa...

Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury

BackgroundThe preferred method of renal-replacement therapy for acute kidney injury in critically ill patients remains uncertain. MethodsIn this multicenter, open-label, noninferiority trial, we randomly assigned critically ill adults with acute kidney injury who had indications...

Transarterial embolization in musculoskeletal care: an indication-stratified narrative review

Abstract Background Transarterial embolization (TAE) is increasingly used across a broad spectrum of musculoskeletal conditions, ranging from established hemostatic and tumor-related indications to emerging pain-directed procedures for degenerative joint disease and chronic infla...

Optimizing the Ocular Surface Before, During, and After Glaucoma Surgery: A Narrative Review

This narrative review synthesizes the published literature on ocular surface disease (OSD) and glaucoma filtration surgery to develop practical, evidence-informed clinical and surgical recommendations for optimizing ocular surface management before, during, and after surgery. The...

Real-World Use of Adjuvant Nivolumab for Resected Stage III–IV Melanoma: 2-Year Analysis of AdjuMel

Following the positive findings of the phase 3 CheckMate 238 trial, adjuvant nivolumab has become a standard therapy in patients with completely resected stage III–IV melanoma. The prospective, ongoing AdjuMel study is evaluating the real-world use, effectiveness, and safety of a...