Hokkaido University of Education

Cytochrome c is Highly Compact upon Transfer into the Gas Phase from Strong Acids as Revealed by High-Pressure ESI Ion Mobility-Mass Spectrometry

Abstract A substantial increase in the acidity of the protein solution (e.g., from pH 2 to pH 1) is known to induce the compaction of fully unfolded proteins, such as cytochrome c, into a non-native yet highly compact molten globule state, referred to as the A-state. In this stud...

Spatiotemporal Distribution of Coseismic Slip During the 2025 Kamchatka Earthquake Inferred from Tsunami Waveform Data

ABSTRACT On 29 July 2025 (UTC), an earthquake with a moment magnitude of approximately 8.8 occurred along the plate interface of the Kamchatka subduction zone and generated a trans-Pacific tsunami. Using tsunami waveform data recorded at offshore stations, we conducted tsunami wa...

Catalyst-Free Dichlorination of Alkenes by Direct Photoexcitation of N-Chloro(fluorenone imine)

A catalyst-free visible-light-induced dichlorination of alkenes has been developed using an N-chloro(fluorenone imine) reagent. The reaction proceeds through direct photoexcitation of the reagent under blue-light irradiation and enables vicinal dichlorination of aliphatic alkenes...

Stringy Constraints on Modular Flavor Models

Abstract We investigate stringy constraints on moduli spaces in modular flavor models by analyzing moduli-dependent threshold corrections in heterotic string vacua. While moduli play a crucial role in determining the flavor structure of fermions predicted by modular flavor models...

Synthetic Study of Mitchellene F by Intramolecular Diels-Alder Reaction

Mitchellenes, isolated from shrubs of the genus Eremophila in Australia, comprise a unique family of sesquiterpenoids, characterized by two, three, or four cyclic systems. The tricyclic mitchellene F was first reported by Greatrex in 2018. In pursuit of the total synthesis of mit...