Hokkaido Information University

Thiophenol-Based Designer Enzymes for Asymmetric Hydrogen/Deuterium Atom Transfer

Abstract The enantioselective control of short-lived radical species in aqueous media represents a major challenge in modern catalysis. Herein, we report on the design and evolution of a designer enzyme with a genetically encoded thiophenol moiety that enables enantioselective hy...

Estimated Dose-Dependent Associations Between Dietary Intake and Stress Responses in Adolescents and Young Adults: Evidence from a Regional Observational Study in Japan

Background/Objectives: The relationship between diet and mental wellbeing is bidirectional: nutritional psychiatry examines effects of diet on mental health, whereas emotional-eating research focuses on the reverse. Although dose–response links between nutrient intake and health...

Effects of daily intake of cacao polyphenols, alone or with milk protein, on skeletal muscle mass in community-dwelling older adults: an exploratory 16-week randomized, open-label, parallel-group trial

Abstract Background Evidence on food-based strategies to maintain muscle-related body composition in older adults under habitual lifestyle conditions is limited. Cacao flavanols may influence vascular and redox pathways, whereas milk protein provides amino acids relevant to muscl...