Hochschule Bielefeld

Multi-lemma representation of Mandarin noun-noun compounds in speech production: EEG evidence

This study investigated how noun-noun compounds and their syntactic properties are represented in production. Participants’ naming latencies and electrophysiological responses were analysed to investigate the classifier congruency effect in Mandarin Chinese (Wang, M., Chen, Y., &...

Bone Radiopharmaceuticals: Evolution from Palliative Therapy to Targeted Precision Oncology and Theranostics

Bone radiopharmaceuticals have evolved from early palliative agents into integral components of targeted precision oncology and theranostics. This review comprehensively traces the historical trajectory, pathophysiological mechanisms, and clinical applications of bone-directed nu...

Post-traumatic stress disorder following intensive care for COVID-19: a single-center retrospective follow-up study

Abstract Background Severe COVID-19 frequently required prolonged intensive care, including mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Survivors of such critical illness may develop post-traumatic stress disorder (PTSD). Methods We conducted a single-ce...

The integration of social determinants of health in antenatal care policies in Brazil: a content analysis of five federal documents

Background Inequities shaped by the Social Determinants of Health (SDH) and intersecting forms of discrimination such as race, age, and socioeconomic status critically influence access to and quality of antenatal care (ANC), a key intervention for preventing maternal mortality. B...

Walking in circles: Linking high- and low-level parameter scaling of visually guided and spontaneous turning behaviour

The ability to change one's current heading, i.e. to turn, is essential for all walking animals. While several studies have addressed how leg movement or inter-leg coordination may change during turning, relatively little is known about how turning-related changes at the level of...

Signals of Communicative Intent Enhance the Impact of Emotional Messages from Human Speakers, While Effects for Robots are Attenuated

Abstract The present work investigated humans’ responses to robots’ verbal emotional expressions. To this end, the interplay of agent characteristics and signals of communicative intent on emotional word processing was examined. In two behavioral studies (N1 = 36, N2 = 72), parti...

Towards a deep-learning genomic tool for risk stratification and diagnostic support in sporadic ALS

Abstract Background A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetic...

Asymptotics of ruin probabilities in a subordinated Cramér-Lundberg model

We study a dynamic model of a non-life insurance portfolio. The foundation of the model is a compound Poisson process that represents the claims side of the insurer. To introduce clusters of claims appearing, e.g. with catastrophic events, this process is time-changed by a Lévy s...

A multilevel analysis of the predictive effects of internal migration and region of residence on women’s empowerment in Nigeria

BACKGROUND: Despite growing research interest on the influences of migration and regions of residence on human behaviors, studies on the influences of migration and region of residence on women empowerment especially in sub-Saharan Africa are lacking. Thus, this study investigate...

From Product-Quality Complaints to Patient-Safety Triage: A Structured Narrative Review and Proposed PRCS-TRACE Framework

Product-quality complaints are usually handled as pharmaceutical quality-system events, yet defects in sterility, potency, identity, packaging, labelling, storage, distribution or delivery-device function may affect medication use, treatment continuity and patient outcomes. This...

Effect of Omani Limestone Waste as a Reinforcing Agent on the Mechanical Properties of Scrap-Based Aluminum Matrix Composites

This paper analyzes the use of Omani limestone, collected from the mountain ranges of the Sultanate of Oman, a major global exporter of limestone, as a natural reinforcement to improve the mechanical properties of recycled aluminum alloys obtained from automotive engine cylinder...

Shifting AAV9 tropism by binding moiety insertion enhances transduction of tumor cell lines and human glioblastoma explants

Abstract Tumor-specific targeting remains a major obstacle for the development of precision cancer therapies. For several tumors and specifically glioblastoma (GBM), an aggressive brain tumor with poor prognosis, more effective treatments are urgently needed. Recombinant adeno-as...

Leveraging Cognitive States for Adaptive Scaffolding of Understanding in Explanatory Tasks in HRI

Understanding how scaffolding strategies influence human understanding in human-robot interaction is important for developing effective assistive systems. This empirical study examines linguistic scaffolding strategies that rely on negation as a key mechanism for steering users a...

The Moment of Delivery in Online Retailing: How Courier Types and Inoculation Messages Affect Reactions to the Last-Mile Experience

Online customers’ journeys span several touchpoints, which typically do not involve any interpersonal interactions with online retailers—except at the moment of delivery (MoD). When retailers use third-party courier services to fulfill orders, they relinquish control over this cr...

From Perceptrons to Convolutional Neural Networks: A Practical Tutorial on Spatial Deep Learning

This tutorial takes the reader on a historical and technical journey from the simple Perceptron (1958) to modern Convolutional Neural Networks (CNNs) that dominate spatial data processing (images and video). We start with the Perceptron’s linear classifier, then expose its inabil...

Ruling In and Ruling Out Sepsis Using Likelihood Ratios of a Host Response Assay

Overview: SeptiCyte RAPID is an FDA-cleared gene expression test that quantifies host immune response to aid in the diagnosis of sepsis. The test yields a score (the SeptiScore) ranging from 0–15, distributed across four bands (1–4) based on increased likelihood of sepsis. Each b...