HM Hospitales

Blood-brain barrier opening with focused ultrasound reduces neuromelanin in a non-human primate model.

Age-related accumulation of neuromelanin (NM) has been implicated in the intrinsic vulnerability of catecholaminergic neurons in Parkinson's disease. Postmortem studies in Parkinson's disease patients have revealed elevated intracellular and extracellular NM in the substantia nig...

Determinants of parental satisfaction in nurse–parent communication during pediatric hospitalization: a systematic review

Children with complex medical conditions require frequent interactions with the healthcare services and multidisciplinary teams. During pediatric hospitalization, effective nurse-parent communication is essential to family experience and satisfaction. To provide a synthesis of th...

Educational and Professional Development Interventions to Strengthen Empathy, Compassion, and Relational Care Among Healthcare Professionals: A Systematic Review

Humanized healthcare depends on professionals’ capacity to communicate empathically, respond compassionately, and establish therapeutic relationships. This globally focused systematic review aimed to synthesize comparative evidence on educational and professional development inte...

Validation of plasma core biomarkers of Alzheimer's disease: A multicenter study in usual practice conditions

Background The new anti-amyloid therapies have brought the challenge of early and feasible identification of Alzheimer's disease (AD). Plasma biomarkers are promising tools, but real-world evidence remains limited. Objective We aimed to evaluate the diagnostic performance of plas...