Henan University

Unveiling the new round of trade-in policies in China: an “objectives-tools-targets” analysis framework

Trade-in policies play an important role in advancing sustainable consumption in China, but their sustained effectiveness still faces obstacles. This study constructs a trade-in policy mix analysis framework, which integrates the three dimensions of policy objectives, tools and t...

A pathological phosphorylation pattern enhances tau cooperativity on microtubules and facilitates tau filament assembly

Abstract Phosphorylation of the microtubule-associated protein tau plays important roles in both normal physiology and disease. While tau phosphorylation levels are similarly elevated in processes such as fetal development and hibernation and in pathological states like Alzheimer...

PGMMF-Net: a POI-Guided Multi-modal Mamba Fusion Network for urban impervious surface extraction from optical and SAR imagery

Accurate extraction of urban impervious surfaces (IS) is essential for urban environmental analysis. However, optical-based methods are affected by shadows and spectral confusion, while optical-SAR fusion lacks urban functional semantics. Point-of-interest (POI) data provide comp...

Genetic Determinants of Milk Production Phenotypes in Dairy Goats: A Review

Dairy goats sustain milk production across marginal environments worldwide, yet genetic improvement of milk yield and composition remains slower than in cattle, constrained by smaller reference populations and limited functional validation. This review consolidates current eviden...

Discovery of serum metabolomics characterization in patients with generalized anxiety disorder based on LC-MS

The pressure on people’s lives and work is increasing with the continuous development of modern society, and generalized anxiety disorder (GAD) has become a relatively common psychological problem. Nevertheless, the pathological mechanisms underlying anxiety disorders remain poor...

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited therapeutic options. The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, activated by cytosolic mitochondrial DNA (mtDNA), has been increasingly implicated in UC. Through p...

Super-resolution downscaling of WRF-based typhoon wind fields over complex coastlines using a decoupled physics-guided U-Net

Accurate kilometer-scale typhoon wind fields are important for coastal hazard assessment, but Weather Research and Forecasting (WRF)-based dynamical downscaling remains computationally expensive, while traditional statistical methods often fail to capture localized topographic ef...

Spatiotemporal-switchable 2D NIR-II single-atom nanozyme for single-cell–level surgical navigation and glioblastoma phototherapy

Single-cell–level resolution tumor therapy represents an advanced strategy against glioblastoma but lacks suitable theranostic agents. Here, we developed a spatiotemporal-switchable, two-dimensional (2D), bismuthene-based second near-infrared window (NIR-II) nanozyme. In this pla...

Spatial-Economic Assessment of Biomass Supply Chains Under Land Fragmentation

Taking Lankao County as a case study, this study extends the established StrawFeed framework by linking NHPI-derived harvest dates to spatially differentiated straw release and seasonal equipment scheduling. Time-series Sentinel-2 observations were used to characterize harvest ti...

Harmony or Conflict? Grandparent–Parent Co‐Parenting Patterns and Children's Problematic Media Use

ABSTRACT Background Grandparent–parent co‐parenting is common in China, but its link to preschoolers' problematic media use is unclear. This study examined how co‐parenting patterns are associated with children's media use, focusing on the mediating role of parental digital paren...

Benzothiazole derivatives target oligoadenylate synthetase and enhance RSV vaccine efficacy as adjuvants

2′,5’ oligoadenylate (2-5A) activates RNase L to degrade intracellular RNA and inhibit viral proliferation. The resulting nucleotide fragments bind RIG-I-like receptors to initiate type I interferon (IFN-I) signaling, enhancing maturation of antigen processing cells to trigger ad...

Tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis of blood loss, transfusion, and deep vein thrombosis

Tranexamic acid (TXA) has been widely used in primary total knee arthroplasty (TKA) to reduce perioperative blood loss, but the pooled evidence regarding blood loss, transfusion, and deep vein thrombosis (DVT) remains to be further clarified. The purpose of this meta-analysis was...

Soil legacy of SiO 2 nanoparticles impedes fall armyworm oviposition by reprogramming constitutive maize volatiles

Abstract BACKGROUND Host–plant selection for oviposition strongly influences herbivorous insect population establishment and crop damage, and is largely mediated by plant volatile cues. Silicon dioxide nanoparticles (SiO 2 NPs) can modify plant–insect interactions, but whether th...