Institution
Helmholtz Institute for RNA-based Infection Research
Recent research
- BiologyOpen access
Post-transcriptional transfer RNA (tRNA) modifications dynamically regulate translational capacity, yet whether the tRNA epitranscriptome is temporally coordinated with gene expression programs during bacterial growth remains unknown. Here, we combine time-resolved nanopore tRNA...
- Health & MedicineOpen access
Cytomegalovirus Latency Fuels Inflammation Following Myocardial Infarction
BACKGROUND: Epidemiological studies have consistently associated cytomegalovirus (CMV) seropositivity with adverse cardiovascular outcomes. However, the mechanisms by which cytomegalovirus infection impacts pathophysiology in the heart remain poorly understood. In this study, we...
- Health & MedicineOpen access
Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells
ABSTRACT Productive human respiratory syncytial virus (RSV) cell entry requires coordinated interactions between viral proteins and host-cell factors at the plasma membrane-actin cortex interface. Branched actin networks remodel this interface, but their precise contribution to t...