Health and Functional Exposomics

Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer

ABSTRACT Human epidermal growth factor receptor 2 (HER2) has emerged as a potential therapeutic target in bladder cancer (BC), particularly with the advent of next‐generation antibody–drug conjugates (ADCs) like trastuzumab deruxtecan (T‐DXd). However, the complex relationship be...

Nuclear activities and interactome of the NS5 protein of tick-borne encephalitis virus

Orthoflaviviruses are RNA viruses responsible for significant diseases in humans, domesticated animals, and wildlife. Their NS5 protein is central in viral replication, functioning both as an RNA-dependent RNA polymerase and a methyltransferase, while also modulating cellular pro...