Hasselt University

Dose-dependent microbiome, metabolome and lipidome shifts in a mouse model of colitis-associated colorectal cancer using azoxymethane and dextran sodium sulphate

Colorectal cancer (CRC) remains a major health burden, underscoring the need for continued research to improve screening methods and treatment outcomes. The colitis-associated azoxymethane (AOM) and dextran sodium sulphate (DSS) mouse model has proven valuable for CRC research, a...

Hypoxia-activated scleraxis a mediates epicardial progenitor differentiation into a unique cardiac perivascular cell type

Abstract The epicardium is a crucial source of progenitor cells and paracrine signals that support heart development and regeneration. However, the molecular mechanisms that guide epicardial cell fate decisions remain incompletely understood. Here, we identify the transcription f...

Integrating road infrastructure condition into intelligent transportation systems: a machine learning-based infrastructure-aware risk prediction approach

Although the majority of Intelligent Transportation Systems (ITS) and risk-prediction frameworks keep considering pavement quality and dynamic traffic behavior as separate phenomena, road infrastructure degradation and traffic flow instability both contribute to risky driving sit...

An UndergraduateBiochemistry Lab Exploring Elastin-LikePolypeptide Behavior and Degradation: From Purification to Proteolysis

Abstract The development of smart biomaterials that mimic the native extracellular matrix forms the basis for many innovations within the field of regenerative medicine. Elastin-like polypeptides (ELPs) are widely used in biomaterials due to their unique physicochemical propertie...

Variations in lower‑limb body composition asymmetry and leg length discrepancy by sex and training level, and their association with performance in recreational endurance runners: a cross‑sectional study

Body composition plays a critical role in endurance running. While anthropometric characteristics have been incorporated into performance prediction models, potential inter-limb morphological asymmetries in lower-limb body composition remain largely unexplored. Therefore, this st...

Modeling local vulnerability to COVID-19 in an outbreak setting

Identifying factors that affect the vulnerability of areas to COVID-19 infection is essential, as it helps to identify the locations or risk groups that require additional attention. While connectivity among regions is a crucial driver in the epidemic growth, it is also observed...

Multilevel structural equation modelling of walkability in a motorcycle-dominated city: A case study of Da Nang, Vietnam

In Southeast Asian cities, rapid urbanisation, characterised by a motorcycle-dominated landscape, has eroded pedestrian infrastructure and compromised walkability. Conventional frameworks, primarily rooted in temperate, car-centric contexts, inadequately capture micro-scale, clim...

Impact of highly intensive functional balance training in children with developmental coordination disorder

Abstract Children with Developmental Coordination Disorder (cDCD) face significant motor coordination challenges, impacting daily activities and participation. This study examined the effects of highly intensive, functional balance training across different levels of the Internat...

Longitudinal characterization of medial gastrocnemius muscle growth deficits throughout childhood in spastic cerebral palsy

The prospective longitudinal study compared muscle growth in children with spastic cerebral palsy (CP) with typically developing (TD) peers and across Gross Motor Function Classification System (GMFCS)-groups, and investigated muscle deficit trajectories across GMFCS-groups. Thre...