Harbor–UCLA Medical Center

Development and Validation of a Coronary Artery Calcium Volume and Density Score

BACKGROUND: Coronary artery calcium (CAC) scoring is a useful tool for coronary heart disease (CHD) risk prediction. The current standard method, the Agatston score, weights plaque area upward by density. However, higher density is inversely associated with CHD. We aimed to devel...

Medical School Performance Evaluations (MSPEs) Lack Objectivity: A Challenge in the Surgery Residency Selection Process

IMPORTANCE In the past several years, the methods used to evaluate medical students have undergone significant shifts. The United States Medical Licensing Examination Step 1 grading has become pass/fail, as has clinical grading at many institutions. Residency program directors ha...

Mucinous Adenocarcinoma Arising in a Mature Ovarian Teratoma.

Malignant transformation of a mature cystic teratoma (MCT) is rare, with mucinous adenocarcinoma being an even more uncommon subtype. Accurate diagnosis requires distinction from metastatic gastrointestinal tumors. A woman in her 30s presented with a 19 cm right ovarian mass. She...

Omic risk scores are associated with COPD-related traits across three cohorts

Background: Chronic obstructive pulmonary disease (COPD) exhibits marked heterogeneity in lung function decline, mortality, exacerbations, and other disease-related outcomes. Omic risk scores (ORS) estimate the cumulative contribution of omics, such as the transcriptome, proteome...

Structural Heart Interventions in Women with Congenital Heart Disease

Abstract Purpose of Review To provide a review of current transcatheter interventions in women with congenital heart disease, with a focus on sex-specific considerations in diagnosis, management, and follow-up. Recent Findings As the field of pediatric cardiology advances and pat...

Changes in Emergency Department Pediatric Readiness, Inpatient Services, and Excess Child Deaths

Importance Emergency department (ED) pediatric readiness and pediatric inpatient services have changed over time in many hospitals, but the impact of these changes on pediatric outcomes is unclear. Objective To evaluate pediatric mortality associated with changes to ED pediatric...