Hanzhong People's Hospital

Association of neoadjuvant subcutaneous trastuzumab with higher pathological complete response in HER2-positive breast cancer: a real-world doubly robust study

Randomized trials have demonstrated the non-inferiority of subcutaneous (SC) versus intravenous (IV) trastuzumab. Its association with pathological complete response (pCR) in routine neoadjuvant practice warrants further study. The ability of serial ultrasound measurements to dis...

A Sensor-Driven State-Space Framework for PM2.5-Informed Natural Ventilation Opportunities Under Coupled Pollution–Thermal–Humidity Constraints

Abstract Natural ventilation can dilute indoor-generated pollutants, but opening windows can also increase coupling to outdoor fine particulate matter (PM 2.5 ). We developed a sensor-driven screening framework that combines sustained outdoor PM 2.5 with a pragmatic temperature–r...

Robust multi-label ECG classification: a deep learning framework for concurrent arrhythmias with clinical generalizability

Electrocardiogram (ECG) signals play a critical role in the clinical screening and diagnosis of various cardiovascular diseases. Although computer-aided diagnostic technologies have alleviated the burden on clinicians, the variability, complexity, and class imbalance of ECG data...

Multi–analytical investigation of Eastern Han gilded copper coffin ornaments excavated from Wushan, Chongqing, China

Abstract Six Eastern Han Dynasty gilded copper coffin ornaments excavated from Wushan, Chongqing, were analysed by optical microscopy, SEM-EDS, and Raman spectroscopy. Results reveal all samples were gilded with mercury amalgam and gilded layer thicknesses ranged from 0.3 to 8.0...

Complete mitochondrial genome assembly and comparative analysis of the endangered species Petrocosmea qinlingensis

Petrocosmea qinlingensis W. T. Wang (Gesneriaceae) is an endemic species from the Qinling Mountains of China . This species has a restricted distribution and a small population size and has been designated as a National Grade II Protected Plant in China. It has attracted taxonomi...

Design and fabrication of a multifunctional Zn-Fe@Ag nanocomposite for effective treatment of infections wounds

<title>Abstract</title> Infectious wounds, a common bacterial infection in clinical practice, often experience significantly delayed healing due to local bacterial colonization, macrophage polarization imbalance, and tissue regeneration inhibition, posing persistent challenges fo...