Hangzhou Academy of Agricultural Sciences

In Situ Tracking of Membrane HER2- Antibody–Drug Conjugate Interaction with Surface PlasmonResonance Imaging

Abstract Antibody–drug conjugates (ADCs) rely on specific recognition of tumor-associated membrane receptors to achieve targeted intracellular drug delivery, yet in situ characterization of their interaction dynamics remains limited. Here, we develop a single-cell plasmonic imagi...

Metal‐Based Combination Therapies in Cancer: Mechanistic Principles and Emerging Opportunities

Metal-based anticancer agents occupy a distinctive niche in cancer therapy owing to their exceptional coordination versatility, redox activity, and tunable photochemical properties, which enable simultaneous engagement of multiple cellular pathways. Despite the clinical success o...