Hamad General Hospital

Fatty liver and adipokines: converging pathways linking insulin resistance to early atherosclerosis in obese children and adolescents

Abstract Introduction Childhood obesity drives nonalcoholic fatty liver disease (NAFLD) and adipokine dysregulation, converging on insulin resistance (IR) to promote subclinical vascular injury measurable as increased carotid intima–media thickness (cIMT). Pediatric-specific mech...

Acute fibrinous and organising pneumonia (AFOP): a case series highlighting diverse aetiologies and clinical outcomes in three patients

Background Acute fibrinous and organising pneumonia (AFOP) is a rare histopathological pattern of acute lung injury characterised by intra-alveolar fibrin deposition and organising pneumonia. It has diverse aetiologies and highly variable clinical outcomes.Case presentations We r...

Neurocognitive outcomes in pediatric brain arteriovenous malformations: a systematic review

Introduction Pediatric brain arteriovenous malformations (AVMs) are an important cause of hemorrhagic stroke and long-term morbidity. Neurocognitive outcomes remain incompletely characterized. Objective To synthesize reported neurocognitive, educational, and occupational outcomes...

Dural Puncture Epidural, Standard Epidural, and No Epidural: Comparative Effects on Labor Progression and Neonatal Outcomes

Objective: To compare non-epidural labor, standard epidural analgesia, and dural puncture epidural analgesia with respect to labor progression, obstetric outcomes, analgesia-related outcomes, and neonatal results. Methods: This single-center retrospective observational cohort stu...

Standard Antiplatelet Therapy Versus Thrombolysis in Acute Spontaneous Spinal Cord Infarction: A Propensity Score–Matched Analysis

BACKGROUND: Spinal cord infarction (SCI) is a rare stroke subtype with no established acute treatment guidelines. Thrombolytic therapy has been used empirically based on extrapolation from cerebral stroke protocols, but comparative effectiveness data are lacking. We compared outc...