Hallym University Sacred Heart Hospital

Short-Term Clinical Outcomes of Ready-Made Soft Splints Versus Digitally Fabricated, Customized Hard Stabilization Splints in Temporomandibular Disorders: An Exploratory Randomized Study

Background/Objectives: Occlusal splints are widely used for temporomandibular disorders (TMDs), but direct evidence comparing ready-made soft splints with customized hard stabilization splints remains limited. This exploratory randomized study compared the short-term clinical out...

Staged bilateral reverse sural artery flap reconstruction for severe frostbite of both feet in a patient with schizophrenia

Rationale: Bilateral, weight-bearing heel defects after frostbite are difficult to reconstruct, and outcomes depend heavily on postoperative off-loading and patient cooperation. We report a limb-salvage strategy for severe bilateral foot frostbite that occurred during acute psych...

Echocardiographic factors suggestive of pulmonary hypertension in patients with mediastinal tumors

Pulmonary hypertension (PH) may occur in diverse clinical contexts. Group 5 PH includes conditions with unclear or multifactorial mechanisms, including tumor-associated PH. Evidence regarding the frequency and clinical significance of elevated right ventricular systolic pressure...

Administration of a phosphodiesterase 4B inhibitor reduces hippocampal neuronal cell death after global cerebral ischemia

Abstract Global cerebral ischemia (GCI) causes widespread neuronal injury, with hippocampal neurons being particularly vulnerable. This study examined whether post-GCI treatment with amlexanox (AMX), a phosphodiesterase 4B (PDE4B) inhibitor, reduces hippocampal neurodegeneration...

Prognostic implications of the duration of continuous kidney replacement therapy in 3-month survivors of acute kidney injury: findings from the LINKA cohort

The duration of continuous kidney replacement therapy (CKRT) represents a complex clinical surrogate reflecting the severity of systemic illness, the rate of metabolic recovery, and clinical decision-making regarding treatment discontinuation. The effect of CKRT duration on long-...

Vascular Imaging Features and Time-Specific Recurrence Risk After Craniocervical Artery Dissection

Background and ObjectivesCraniocervical artery dissection (CCAD) is a major cause of stroke in young adults, yet its recurrence risk remains poorly defined because of delayed enrollment in prior research. We aimed to determine the temporal distribution of recurrent ischemic strok...

Per Protocol Analysis and Long‐Term Outcomes of Laparoscopic Radical Resection for Gallbladder Cancer Compared With Open Method

BACKGROUND: Although laparoscopic radical resection for gallbladder (GB) cancer has been attempted, only a limited number of studies have evaluated its outcomes using a per-protocol analytical approach. METHODS: Between January 2010 and December 2019, 213 patients underwent surge...

Prenatal PM2.5 exposure drives epigenetic reprogramming of fetal macrophages linked to atopic dermatitis

Abstract Prenatal environmental exposures are increasingly recognized as contributors to atopic dermatitis (AD), yet the underlying mechanisms remain unclear. Fine particulate matter (PM 2.5 ), a complex mixture of airborne pollutants, has been associated with elevated risk of al...