Institution
Hallym University
Recent research
- Health & MedicineOpen access
Background/Objectives: Occlusal splints are widely used for temporomandibular disorders (TMDs), but direct evidence comparing ready-made soft splints with customized hard stabilization splints remains limited. This exploratory randomized study compared the short-term clinical out...
- Health & MedicineOpen access
Rationale: Bilateral, weight-bearing heel defects after frostbite are difficult to reconstruct, and outcomes depend heavily on postoperative off-loading and patient cooperation. We report a limb-salvage strategy for severe bilateral foot frostbite that occurred during acute psych...
- BiologyOpen access
Circadian misalignment and low-grade inflammation: Failure of temporal gating by the molecular clock
Circadian misalignment, from shift work, recurrent sleep-wake disruption, or mistimed behavioral rhythms, tracks with cardiometabolic disease and low-grade systemic inflammation, yet no single account ties the molecular, animal, and human evidence together. This narrative review...
- AI & ComputingOpen access
Abstract Preoperative computed tomography (CT) is routinely acquired for planning robotic-assisted total knee arthroplasty (TKA), yet osteophyte burden is not quantitatively characterized. We developed automated CT-based osteophyte quantification and evaluated it against blinded...
- Climate & EnvironmentOpen access
Drivers governing the seasonality of new particle formation in the Arctic
New particle formation (NPF) is the phenomenon wherein gaseous precursors form critical clusters of barely a few nanometres in diameter, after which, under favourable conditions, these particles can grow to climate-relevant sizes. Here we present measurements from 2022 to 2024 of...
- Health & MedicineOpen access
The 2025 Korean pediatric advanced life support guideline update introduces clinically important revisions emphasizing airway strategy, physiologic resuscitation targets, post-cardiac arrest hemodynamics, neuroprotection, and extracorporeal support. In out-of-hospital pediatric c...
- Health & MedicineOpen access
Pediatric cardiac arrest primarily arises from asphyxia in infants and trauma in older children, contrasting with adult etiologies dominated by cardiac events. This underscores prevention as the cornerstone of pediatric basic life support, through injury mitigation like child res...
- Health & MedicineOpen access
The 2025 Korean Guidelines for Cardiopulmonary Resuscitation provide updated, evidence-based recommendations to optimize the transition from intrauterine to extrauterine life. While approximately 85% of term newborns initiate spontaneous breathing independently, timely interventi...
- BiologyOpen access
Abstract Global cerebral ischemia (GCI) causes widespread neuronal injury, with hippocampal neurons being particularly vulnerable. This study examined whether post-GCI treatment with amlexanox (AMX), a phosphodiesterase 4B (PDE4B) inhibitor, reduces hippocampal neurodegeneration...
- BiologyOpen access
The genus Alphacoronavirus (α-CoV), belonging to the family Coronaviridae , comprises positive-sense RNA viruses that infect a broad spectrum of mammalian hosts, often facilitating cross-species transmission. Bats are recognized as the ancestral reservoirs for numerous α-CoVs tha...
- BiologyOpen access
Abstract Extracellular vesicle (EV)-derived microRNAs are promising non-invasive biomarkers for colorectal cancer (CRC), but their stage-specific prognostic significance remains unclear. We evaluated circulating EV-derived miR-4435 and its target TIMP3 in a retrospective cohort o...
- Biology
Background Hospitalisations represent major clinical events in cirrhosis, yet prediction based on clinical variables alone remains limited. Objective Given the role of the gut microbiome in disease progression, we evaluated whether gut metagenomic profiles are associated with 90-...
- Health & MedicineOpen access
Post-burn hypertrophic scar (HTS) formation is influenced by the dynamic balance between keratinocyte proliferation and differentiation, a process critical for maintaining skin homeostasis. Serine/threonine kinase 33 (STK33) has emerged as a potential therapeutic target in oncolo...
- Society & Economics
When good intentions backfire: the paradoxical effects of CSR fit in stigmatized industries
Purpose This study aims to investigate why corporate social responsibility (CSR) initiatives from stigmatized industries often fail despite genuine efforts, examining how industry identification and product-cause fit influence consumer responses. Using the Persuasion Knowledge Mo...
- Health & MedicineOpen access
A 65-Year-Old Man With Abdominal Pain, Duodenal Ulceration, and Skin Lesions
QuestionA 65-year-old man with hypertension presented to the emergency department with one month of persistent abdominal pain and postprandial distress that had not improved despite two hospitalizations at an outside clinic.One month before the current admission, he had developed...
- Physics & SpaceOpen access
Physics-Informed and Data-Driven Forecasting of Chaotic Dynamics Across Lorenz and Rössler Systems
Reliable finite-horizon forecasting of chaotic dynamics is challenging because small approximation errors grow rapidly during recursive prediction. This study presents a controlled comparison of data-driven and physics-regularized forecasting methods for the Lorenz and Rössler sy...
- Health & MedicineOpen access
Background/Aims: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely prescribed for type 2 diabetes and obesity. Gastrointestinal adverse events are common; however, the association with gastroesophageal reflux disease (GERD) has not been validated across diverse pop...
- Health & MedicineOpen access
Obesity is a major risk factor for non-communicable diseases and mortality. This study aimed to examine the associations between ultra-processed food intake and the risks of obesity and weight gain, and to evaluate whether these associations differed by polygenic scores for obesi...
- Health & MedicineOpen access
Study DesignPost hoc analysis.ObjectiveTo determine whether Meyerding grade I degenerative spondylolisthesis (DS1) modifies 12-month clinical or radiographic outcomes after biportal endoscopic laminectomy (BE-L) versus microscopic laminectomy (M-L) for lumbar spinal stenosis, and...
- Engineering & TechnologyOpen access
Abstract Multicellular tumor spheroids (MTS) are widely used three-dimensional tumor models in various biomedical fields. Despite the increasing use of MTS, systematic comparisons providing practical information for selecting fabrication platforms according to experimental object...