Hallym University

Comparative evaluation of multicellular tumor spheroid fabrication platforms for reliable drug screening

Abstract Multicellular tumor spheroids (MTS) are widely used three-dimensional tumor models in various biomedical fields. Despite the increasing use of MTS, systematic comparisons providing practical information for selecting fabrication platforms according to experimental object...

Short-term knowledge gains and learner satisfaction after a basic radiology course for family medicine residents in a 3-dimensional virtual environment: a multi-cohort pretest–posttest study in Spain

Purpose: This study aimed to evaluate a structured basic radiology course for Family Medicine residents delivered in a 3-dimensional (3D) virtual environment (Second Life). We hypothesized that participation would be associated with higher post-course knowledge test scores and hi...

An autoinflammatory CDC42 variant M45L demonstrates the mechanism of pyrin inflammasome activation

CDC42 is an evolutionarily conserved guanosine triphosphatase (GTPase) regulating critical cellular and immune processes. Variants in CDC42 therefore cause a spectrum of developmental phenotypes, including hematological and immunological symptoms. Here, we identify a previously u...

Cognitive Workload and Mental Burden in Health Care Professionals Interacting With AI: Systematic Review and Meta-Analysis

Background: AI adoption in health care has accelerated rapidly, with ambient documentation tools, diagnostic imaging AI, and clinical decision support systems (CDSSs) entering routine practice. However, the cognitive demands placed on clinicians supervising these systems remain u...