Hainan Provincial Hospital of Traditional Chinese Medicine

Neoadjuvant Anbenitamab and HB1801 in ERBB2 -Positive Breast Cancer

IMPORTANCE The combination of neoadjuvant taxanes with trastuzumab and pertuzumab remains the cornerstone treatment strategy in ERBB2 -positive breast cancer. Anbenitamab (a ERBB2 -biparatopic antibody that induces profound receptor clustering) and HB1801 (a solvent-free albumin-...

Walking the tightrope: Mixed respiratory failure exacerbated by heart rate control and concurrent pneumonia in an elderly patient with new-onset atrial fibrillation

Rationale: The interplay between new-onset atrial fibrillation (AF), heart failure (HF) with preserved ejection fraction (HFpEF), and acute infection in the elderly presents a complex clinical challenge. Rate control is a cornerstone of AF management, but its application in frail...