Hainan Modern Women and Children's Hospital

Maternal and fetal risk factors for hypospadias: a hospital-based case-control study in Southern China

Hypospadias is a frequent congenital anomaly in male infants, defined by the urethral meatus opening on the ventral surface of the penis. Although its causes have been examined for many years, the underlying aetiology in most affected children remains unclear. Maternal factors su...

Single-cell transcriptomics uncovers HPV-driven immune evasion and establishes a TAB2-based prognostic signature in cervical cancer

Background Persistent human papillomavirus (HPV) infection is a key driver in cervical cancer, yet the molecular mechanisms linking HPV to immune escape remain incompletely understood. Methods We integrated single-cell RNA sequencing (scRNA-seq), bulk transcriptome, and clinical...