Hackensack University Medical Center

Cyclosporiasis in Pregnancy: A Narrative Review

Objective: Cyclosporiasis, caused by the protozoan parasite Cyclospora cayetanensis, is an emerging foodborne illness of increasing clinical relevance in both endemic and developed countries. Its specific implications during pregnancy remain poorly characterized. Our objective is...

Routine Serologic Duffy Testing in Pediatric Oncology: Clinical Utility and Feasibility in a Single‐Center Cohort

ABSTRACT Background Absolute neutrophil count (ANC) guides chemotherapy dosing, treatment timing, and clinical trial eligibility throughout pediatric oncology. Duffy‐null‐associated neutrophil count (DANC) is a physiologic variant characterized by lower ANC that may be misinterpr...

Commissioning and end‐to‐end validation of a combined surface‐guided and triggered kV imaging workflow for breath‐hold SBRT on a Varian TrueBeam

Abstract Background Respiratory motion introduces significant geometric uncertainty in Stereotactic Body Radiotherapy (SBRT) for thoracic and abdominal tumors. Deep Inspiration Breath‐Hold (DIBH) mitigates this, but the surface signal alone may not reflect internal target positio...

High-grade astrocytoma with piloid features: a clinical and genomic analysis of prognostic factors using a large cohort

BACKGROUND: High-grade astrocytoma with piloid features (HGAP) is a recently defined tumor type that is not well-understood. Prognostic factors of clinical outcomes are not well-established. METHODS: Methylation profiling was performed on tumor samples, many at the National Cance...

Large language models for tympanostomy patient education: readability and guideline adherence

Abstract Purpose To evaluate the accuracy and readability of large language model (LLM)-generated patient education materials regarding tympanostomy tube placement. Methods Over a two-month period, ChatGPT 4o, Gemini 2.5 Flash, and Google Search AI were prompted daily using long-...

When Empiric Therapy Fails: Clinical and Economic Consequences in uUTIs Among US Women

Uncomplicated urinary tract infection (uUTI) management is increasingly challenging due to antibiotic treatment failure (TF). This retrospective, observational cohort study used Optum’s de-identified Electronic Health Record dataset (January 2017–September 2022) to investigate th...

Intraoperative Factors Associated With Postoperative Febrile Infectious Complications Following Retrograde Intrarenal Surgery: A Propensity Score-Matched Study

Purpose: To investigate the intraoperative factors associated with postoperative febrile infectious complications following retrograde intrarenal surgery (RIRS).Materials and Methods: A total of 352 patients who underwent RIRS for renal stones between March 2017 and December 2022...

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

Cell‐free RNA (cfRNA) is emerging as a supplemental approach for liquid biopsy (LBx). Given that lymphoid cells and plasma cells express substantial quantities of immunoglobulin (Ig) and T‐cell receptor (TCR) RNA, we investigated the utility of using cfRNA for detecting B‐cell an...

Multidisciplinary Approaches to the Management of Spinal Care: A Narrative Review

Abstract For patients with spinal care conditions including degenerative disease, deformity, traumatic injury, and complex pain syndromes, care is frequently fragmented across multiple specialists. This process can delay diagnosis, create complexity in communication, and result i...