Guizhou Center for Disease Control and Prevention

Associations of Distinct Dietary Indices with Global and Domain-Specific Cognition and Age-Related Heterogeneity in Older Chinese Adults

Background: Whether distinct dietary indices are similarly associated with cognitive domains and whether these associations vary by age remain unclear. We examined the Chinese MIND diet score (cMIND), dietary diversity score, and healthy plant-based diet index (HPDI) in relation...

Macroscopic and mesoscopic mechanical behavior of the interface between piles and unsaturated sand under vertical cyclic loading

Understanding the degradation of pile bearing capacity under vertical cyclic loading requires an in-depth investigation of the pile–unsaturated sand interface. This study employs a multi-scale approach—combining visualized cyclic loading tests, particle image velocimetry (PIV), a...

Genomic characteristics and evolutionary analysis of Bordetella pertussis in Guizhou Province, China

Abstract Background Pertussis is an acute infectious respiratory disease caused by Bordetella pertussis (Bp). Despite high vaccination coverage, the genome of B. pertussis is prone to variations. These variations can lead to vaccine immune escape, recurrence of outbreaks, and inc...

Genetic diversity, drug resistance, and molecular transmission networks of HIV-1 in Zunyi: implications for precision prevention

Abstract Background HIV-1 genetic diversity and the spread of pretreatment drug resistance (PDR) complicate epidemic control. Southwestern China has a heterogeneous HIV epidemic, but molecular transmission dynamics in many prefecture-level settings remain poorly described. Method...

Prevalence of Keshan disease at the township level in China: a cross-sectional study

Keshan disease (KD), an endemic myocardiopathy with unclear etiology, lacks primary preventive measures. This study aimed to assess the prevalence of KD at the township level using spatial epidemiology, elucidate its distribution characteristics for further precision classificati...