Guigang City People's Hospital

The marine drug plitidepsin alleviates osteoporosis in estrogen-deficient mice by suppressing ROS-mediated NRF2/HO-1 signaling and osteoclast formation

Abstract Marine-derived compounds represent an important source of innovative therapeutics owing to their structural diversity and broad bioactivity; however, their potential in osteoporosis therapy remains insufficiently explored. This study investigated the effects of plitideps...

Habitat-Associated Variation in Dietary Composition, Gut Microbiota, and Muscle Nutritional Characteristics of Hemibagrus guttatus in a Dam-Regulated River

Hydropower regulation can alter riverine habitats and potentially influence fish diet, gut microbiota, and nutritional characteristics. In this study, upstream and downstream populations of Hemibagrus guttatus (H. guttatus) were investigated in a dam-regulated reach of the Hongsh...

A Swirl-Driven Grouting Control Method for Non-Newtonian Fluids: 2.5D Seepage Model and Stability Analysis of Fractal-like Viscous Fingering

In porous media grouting, highly viscous non-Newtonian fluids often trigger viscous fingering (Saffman–Taylor instability) due to adverse mobility ratios, creating fractal-like preferential channels that severely weaken the reinforcement volume. To overcome this, a novel swirl-dr...

Effects of Supplementation with Different Concentrations of Selenium on Fruiting Bodies and Substrate Microbial Community Dynamics in Pleurotus ostreatus Cultivation

To investigate the effects of substrate selenium on mushroom growth, nutritional quality, and associated microbial community structure, the thermo-tolerant Pleurotus ostreatus cultivar “Daye 39” was used as the experimental material. Sodium selenite was applied at gradient concen...