Guangzhou Electronic Technology (China)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Ventilator-induced lung injury (VILI), an iatrogenic complication of mechanical ventilation, remains poorly understood due to the absence of physiologically relevant in vitro models, impeding targeted therapy development. Here, we engineer a bioinspired acinus-on-a-chip model rec...