Guangxi Maternal and Child Health Hospital

Clinical phenotype, family segregation, and follow-up of pediatric distal renal tubular acidosis associated with a homozygous SLC4A1 p.G701D variant

<title>Abstract</title> <bold>Background</bold> We report a case of SLC4A1-related distal renal tubular acidosis (dRTA) in a child with marked skeletal deformities, confirmed by family segregation analysis, and describe the clinical features, genetic findings, and follow-up chang...

A nomogram for distinguishing ovarian endometrioma in patients with endometriosis: a retrospective study based on clinical indicators

Among the subtypes of endometriosis (EMs), ovarian endometrioma (OE) causes the most direct and progressive damage to ovarian reserve function. This study aimed to identify independent risk factors for OE in patients with EMs, and to develop and validate a clinical classification...

Calcium Phosphate Nanoparticle Delivery of siTRIB3 Inhibits EMT and Stemness in NSCLC

Background: TRIB3 is upregulated in non-small cell lung cancer (NSCLC) and associates with worse survival, yet targeted therapeutics remain lacking. Calcium phosphate (CaP) nanoparticles offer biocompatible, serum-stable delivery for siRNA therapy. Here, we developed CaP nanopart...