Guangdong Provincial Hospital of Traditional Chinese Medicine

A review of power conversion and energy management technologies in rheumatoid arthritis diagnostic equipment

Purpose This study aims to investigate electrical energy management challenges across rheumatoid arthritis (RA) diagnostic devices, addressing a critical gap between large high-resolution imaging equipment and portable microsystems. The research seeks new insights into key power...

Efficacy and safety of Shenfu injection on sepsis-induced myocardial dysfunction: a meta-analysis and trial sequential analysis

The efficacy and safety of Shenfu Injection (SFI) as an adjunctive treatment for sepsis-induced myocardial dysfunction (SIMD) remain uncertain despite preliminary investigations. Eight databases were searched for qualified randomized controlled trials (RCTs) from inception to 10...

Interpretable machine learning model for predicting the ICU readmission of patients after coronary intervention

To develop and validate an interpretable machine learning (ML) model integrated with inflammatory indicators for predicting ICU readmission in patients after coronary intervention (PCI/CABG). We used retrospective data from MIMIC-IV (training, 2196 patients) and MIMIC-III (extern...

52‐week ivarmacitinib in moderate‐to‐severe atopic dermatitis: A phase 3 trial

BACKGROUND: Ivarmacitinib, an oral JAK1 inhibitor, improved efficacy outcomes versus placebo at Week 16 in a phase 3 trial in patients with moderate-to-severe atopic dermatitis (AD). OBJECTIVES: To describe efficacy and safety outcomes through Week 52. METHODS: In this multicentr...

Baseline airway dysfunction and small-airway abnormality burden are longitudinally associated with adverse ultradistal radial bone density outcomes in a 5-year cohort

Impaired pulmonary function has been linked to lower bone mineral density and higher fracture risk, but longitudinal evidence on airway dysfunction and subsequent peripheral bone-density outcomes remains limited. We investigated whether baseline airway dysfunction, FEV1/FVC, and...

Increased number of cells in day 3 embryosis associated with higher live birth rate in D5 vitrified–thawed single blastocyst transfer cycles

Cell number in 3-day-old (D3) embryos influences pregnancy outcomes in patients undergoing cleavage-stage embryo transfer. However, the association between D3 cell number and pregnancy outcomes following 5-day-old (D5) vitrified–thawed single blastocyst transfer remains underexpl...

IS 26 -mediated circular bla KPC transposon in ST2483 Pseudomonas aeruginosa

ABSTRACT The global spread of carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a critical clinical threat, with bla KPC as a key mobile carbapenem resistance gene. Here, we investigated a novel bla KPC-2 genetic element and its transmission in clinical ST2483 isolate PA10...