Guangdong Province Stomatological Hospital

Knowledge and attitudes about artificial intelligence and its applications among Chinese endodontic practitioners: a cross - sectional survey

Artificial intelligence (AI) has been increasingly applied in dentistry, including cariology and endodontics. However, evidence remains limited regarding endodontic practitioners’ AI literacy, perceptions, clinical usage, and barriers to AI integration. This study aimed to invest...

Light‐Synergistic Enhanced Synaptic Devices Toward Superadditive In‐Sensor Computing

ABSTRACT Conventional neuromorphic devices face challenges in achieving efficient integration of light sensing and synaptic computation because of structural and material limitations. In this work, we developed an indium‐tin‐zinc oxide/transparent gelatin electrolyte synaptic tra...

Perioperative prediction of ideal postoperative recovery after kidney transplantation: a multicenter retrospective cohort study

Kidney transplantation is the preferred treatment for end-stage renal disease, but early postoperative outcomes remain heterogeneous. Textbook outcome (TO), a composite measure of an ideal postoperative recovery trajectory, has emerged as a meaningful indicator of surgical qualit...

Inhibition of Jaw Bone Marrow Mesenchymal Stem Cell Cuproptosis Attenuates Bone Loss in Apical Periodontitis via Suppressing the FoxO Signalling Pathway

ABSTRACT Aim Apical periodontitis (AP) is an infectious disorder characterized by periapical inflammation and alveolar bone destruction. Recent evidence suggests that cuproptosis, a distinctive form of copper‐regulated cell death, has been implicated in the regulation of bone los...

Sprayable hydrogel loaded with engineered fusion cellular vesicles for cancer recurrence suppression

Surgical resection often leaves residual lesions that lead to tumor recurrence and high mortality across various cancer types, a challenge that is particularly pronounced in oral squamous cell carcinoma. Herein, we developed a sprayable hydrogel loaded with fusion cellular vesicl...

Evaluating global clinical trials and development trends of antibody-drug conjugates

Antibody-drug conjugates (ADCs) represent a breakthrough in tumor-targeted therapy, showing promise in both solid tumors and hematological malignancies. By 1 September 2025, more than 370 ADC candidates had entered clinical development, 17 unique products had received at least on...

WDR4-mediated m7G modification of ZBP1 mRNA drives peri-implantitis by promoting M1 macrophage polarization

Abstract Objective Macrophage polarization exerts a vital role in the progression of peri-implantitis. RNA methylation serves as an important regulator of macrophage polarization. However, reports on the role of N7-methylguanosine (m7G) regulators in peri-implantitis are scarce....

Systemic influences on orthodontic tooth movement: mechanisms and clinical implications

Orthodontic tooth movement (OTM) is a complex biological process involving bone remodeling, which can be significantly affected by systemic diseases and systemic factors. This review comprehensively examines how systemic conditions such as diabetes mellitus, thyroid dysfunction,...