Guang Fu Hospital

Observed CTIT onset timing is associated with platelet surveillance schedules in a real-world cohort

Chemotherapy-induced thrombocytopenia (CTIT) is detected through platelet testing, so routine-care estimates of onset and recovery may depend on surveillance schedules. We characterized within-cycle timing and assessed whether apparent differences among drug categories persisted...

Senescence-related immunosuppressive gene MFAP2 orchestrates stromal-immune crosstalk and immunotherapy resistance in gastric cancer

Abstract Background Gastric cancer (GC) is a leading cause of cancer-related mortality worldwide, with poor prognosis and immune checkpoint inhibitor (ICI) resistance mediated by immune escape. Senescence-related immunosuppressive genes (SRIGs) regulate the tumor microenvironment...