Groupe Hospitalier Diaconesses Croix Saint-Simon

The Role of Artificial Intelligence in Optimizing Diagnosis in Prostate Cancer—A Narrative Review

Artificial intelligence (AI) is increasingly being investigated in prostate cancer (PCa) diagnosis and characterization, offering novel approaches to improve detection and risk stratification. This narrative review summarizes current evidence regarding the application of AI acros...

An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation

Heterozygous carboxyl-terminal variants in the RHO guanosine triphosphatase (GTPase) CDC42 are known to cause severe autoinflammatory syndromes. Here, we identified a heterozygous amino-terminal p.T43I (Thr 43 →Ile) CDC42 variant in patients with autoinflammation and uncovered a...