Green Valley High School

Joint molecular optimization for efficient virtual screening via machine learning

Joint molecular optimization serves as the central focus of this research, which explores the synergistic integration of machine learning (ML) and virtual screening (VS) for drug discovery. This study addresses these limitations by integrating molecular docking and ML to predict...

Phone Physics and the Gateway Arch: Fun with Friends and Physics at the AAPT Winter Meeting in St. Louis

As a famous landmark and feat of engineering, the Gateway Arch was a popular destination at the 2025 AAPT Winter Meeting in St. Louis. The visit to the observation deck of the Gateway Arch is unique, climbing the steps after exiting the small tram capsules and seeing a floor that...

What a slice-level benchmark certifies without the pixels: a label-file audit of seven public benchmarks, and a protocol-frozen random-sample screen of how often the check is reported

Background. Volumetric images are often labelled and scored one slice at a time. Shortcut learning, acquisition confounding and the inflation caused by slice-level splits are documented, and a pixel-free positional baseline is itself prior art; what is unmeasured is how much of a...

What a slice-level benchmark certifies without the pixels: a label-file audit of seven public benchmarks, and a protocol-frozen random-sample screen of how often the check is reported

Background. Volumetric images are often labelled and scored one slice at a time. Shortcut learning, acquisition confounding and the inflation caused by slice-level splits are documented, and a pixel-free positional baseline is itself prior art; what is unmeasured is how much of a...