Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals

Latent tuberculosis infection shapes gut microbiome and immune-metabolic interactions in people living with HIV

The silent presence of latent tuberculosis infection (LTBI) in people living with HIV (PLHIV) increases the annual risk of tuberculosis (TB) reactivation by 3%–16%. Although gut dysbiosis is well documented in HIV, microbiome alterations associated with LTBI in PLHIV remain poorl...