Grade Medical (Czechia)

Immediate Versus Early Loading Protocols in Rehabilitation of Fully Edentulous Maxilla: A 5‐Year Pilot Randomized Clinical Trial

ABSTRACT Objective To compare 5‐year outcomes of immediate versus early loading protocols for complete implant‐supported fixed dental prostheses in edentulous maxillae. Materials and Methods A prospective randomized controlled trial evaluated 24 patients (144 Bone Level Tapered S...

Injectable platelet-rich fibrin improves clinical, biochemical, and microbiological outcomes in periodontitis: a 6-month split-mouth randomized controlled trial

The study aimed to investigate the effects of scaling and root planing (SRP) in conjunction with injectable platelet-rich fibrin (i-PRF) in patients with periodontitis (Stage II–III, Grade B) 1, 3 and 6 months following the treatment. Using the “split-mouth” design, 30 patients w...

Integrated Chemical, Computational, and Cellular Profiling of a Dual-Oil Melanoma Formulation: An Exploratory Life-Science Study

Background: Previous studies have examined bioactive constituents of Prunus dulcis oil, Pinus sylvestris essential oil, and related phytochemical matrices separately; however, their combined chemical profile, comparator-context molecular-docking landscape, and comparative cellula...