Government Medical College

Lactation Failure in Postpartum Women Receiving a Dopamine Partial Agonist During Pregnancy

Background Third-generation antipsychotics like aripiprazole can suppress prolactin secretion via the tuberoinfundibular pathway, leading to postpartum lactation failure. This case series assesses the clinical management of this under-recognized postpartum complication in women w...

Cardiac cirrhosis and portal hypertension as initial manifestations of undiagnosed adult atrial septal defect with Eisenmenger physiology: a case report

Atrial septal defect (ASD) is a congenital cardiac anomaly that may remain clinically silent until adulthood, potentially progressing to serious complications if undiagnosed. Cardiac cirrhosis and portal hypertension as initial manifestations of undiagnosed ASD with Eisenmenger p...

A retrospective study on cost analysis and drug utilization among indoor patients of schizophrenia at psychiatric department of tertiary care hospital of South Gujarat

Abstract Background: Schizophrenia is a chronic psychiatric illness requiring long-term drug therapy. Rational and economical use of antipsychotics is essential to optimize treatment outcomes, especially in developing countries like India. Objectives: To evaluate the drug utiliza...

Rethinking the role of citations in peer review priorities: A perspective

Peer review is intended to assess the scientific quality of research based on its content, including the importance of the research question, appropriateness of methods, validity of the analysis, and strength of the evidence. Citations play an important role in this process by pl...

A novel approach to dyslexia detection: combining EEG data and cognitive tasks with advanced machine learning

Existing dyslexia detection methods typically rely on either EEG or screening tests. This study introduces a multimodal two-stage methodology for dyslexia detection that integrates both EEG signals and screening test data, using spectral features (Shannon entropy and Power Spectr...

IIoT-Based Automated Environmental Control and Quality Tracking System for Food Processing and Storage Facilities

Abstract Keeping perishable food safe, fresh, visually appealing, and nutritionally dense throughout the complex journey from initial agricultural harvest, through heavy industrial processing, and into commercial cold storage warehouses requires rigorous, minute-by-minute regulat...

THE IMPACT OF GLP-1 RECEPTOR AGONISTS ON METABOLIC AND REPRODUCTIVE OUTCOMES IN POLYCYSTIC OVARY SYNDROME

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder characterised by a constellation of reproductive, metabolic, and hormonal abnormalities. This review evaluates the mechanism of action and efficacy of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in managi...

Circulating microRNAs: a new era in early detection of oral squamous cell carcinoma (OSCC) — a systematic review and meta-analysis

BACKGROUND: The chances of oral squamous cell carcinoma (OSCC) being diagnosed at an early stage are very low, and this leads to a poor prognosis. The presence of circulating miRNAs (miRNAs) in blood or saliva is now a potential non-invasive diagnostic biomarker, although the dia...

Transforming thalassaemia care in India through virtual capacity building: Evolution of a national training initiative using extension for community healthcare outcomes model

BACKGROUND AND OBJECTIVES: India has one of the world's highest burdens of thalassaemia, with 10,000-15,000 births annually and a carrier prevalence of 3%-4%. Services for prevention and comprehensive care remain fragmented, especially in rural regions. To address gaps in provide...