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Network Pharmacology and Systems-Level Deconstruction of Multi-Target Phytochemicals from Ocimum sanctum against the HIV-1/Host Interactome: A Dual Virology-Metabolic Interface Study

Background: Human Immunodeficiency Virus Type 1 (HIV-1) systematically alters host cellular networks, triggering chronic hyper-inflammation while aggressively disrupting host lipid and glucose pathways (Arya et al., 2024; Kondapalli et al., 2022). While conventional antiretrovira...