Golestan University

Treatment-associated changes in SESN2, NFATC1, and NRF2 gene expression in rheumatoid arthritis: a comparative study of newly diagnosed and DMARD-treated patients

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by uncontrolled joint inflammation and progressive structural damage in the joints. Sestrin 2 ( SESN2 ) and nuclear factor erythroid-related 2 ( NRF2 ) acts as critical regulators of cellular redox homeostasis and...

Association between preoperative hypoalbuminemia and postoperative complications in spinal fusion surgery: an approach- and spinal level-stratified meta-analysis

While hypoalbuminemia is recognized as a risk factor for adverse postoperative outcomes in various surgeries, its specific impact on spinal fusion outcomes has not been systematically synthesized. This meta-analysis aimed to evaluate the association between preoperative hypoalbum...

Diffusion tensor tractography of the corpus callosum in major depressive disorder: a case-control study

Major Depressive Disorder (MDD) is a common and disabling psychiatric disorder that has been associated with alterations in white-matter microstructure, including abnormalities of the corpus callosum. This study aimed to compare the brain tracts of the corpus callosum using diffu...