Gold Coast Hospital

Reproducibility of Cervical Strain Elastography Using a Standardized Acquisition Protocol in Mid‐Trimester Pregnancy

ABSTRACT Objective To evaluate the intra‐and interobserver reproducibility of the cervical elastography index (EI) measurements using strain elastography (SE) with a standardized acquisition protocol. Methods In this prospective cross‐sectional study, 301 women between 18 and 24...

Fibrinogen Early In Severe Trauma studY II (FEISTY II): study protocol for a randomised clinical trial of fibrinogen concentrate vs cryoprecipitate in traumatic haemorrhage in Australia and New Zealand

Haemorrhage is a leading cause of preventable death amongst severe trauma patients and is often complicated by hypofibrinogenaemia. Fibrinogen replacement can be achieved using fibrinogen concentrate (FC) or Cryoprecipitate (Cryo), but comparative evidence in traumatic haemorrhag...

Functional causes of low testosterone predominate in contemporary Australian endocrine referral practice: a two centre experience across 5 years

Abstract Background The epidemiology and outpatient management of low testosterone in Australian tertiary care remain poorly characterised. Rising testosterone prescription rates and evolving guidelines underscore the need to delineate contemporary referral patterns, diagnostic a...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...