Gold Coast Health

Feasibility of implementing a mindfulness-based program for paediatric intensive care unit staff

Background Paediatric intensive care unit (PICU) clinicians are particularly susceptible to workplace stress due to frequent ethical dilemmas (for example, perceptions of futile or unethical treatment), patient morbidity and mortality, sleep disruption, and emotional exhaustion,...

Rehabilitation management of children with hereditary spastic paraplegia: a retrospective cohort study

Background Hereditary spastic paraplegia (HSP) is a group of rare, genetically heterogeneous neurodegenerative conditions characterized by progressive lower limb spasticity. In children, rehabilitation management of HSP is commonly extrapolated from cerebral palsy practice, despi...

Corticosteroid use in children with community acquired sepsis: a multicentre prospective cohort study

Objectives Corticosteroids in paediatric sepsis have the potential to improve outcomes, yet there is little supporting evidence regarding efficacy, choice of agents, dose or timing of administration. We describe the patterns of corticosteroid use in children hospitalised with sus...

Clearance of Treponema pallidum from oral and anal sites after treatment of secondary syphilis: results from a multi-centre, prospective, cross-sectional study

Background Syphilis is increasing worldwide, and secondary syphilis may represent its most infectious stage. Scarce data exist on Treponema pallidum clearance after treatment. We aimed to determine the frequency and load of T. pallidum mucosal shedding, and time to clearance foll...

Osteoporosis treatment with biosimilars in Malaysia and Thailand: a budget impact analysis

Abstract Introduction Biologic treatments demonstrate long-term clinical benefits for patients with osteoporosis, but their cost is prohibitive, and access can be limited, particularly in low-income countries. This analysis determined the cost impact of introducing biosimilar den...

Stakeholder perspectives on the development of a school based mental health programme in Bangladesh: a qualitative needs assessment

Abstract Background Bangladesh, a South Asian country where approximately one-third of the population comprises children and adolescents, has an estimated prevalence of mental disorder of 13.6% among this age group, while the treatment gap remains as high as 94.5%. A whole-school...