GGD Amsterdam

Post-acute sequelae of COVID-19 (PASC) are associated with distinct clinical phenotypes two years after SARS-CoV-2 infection: A data-driven approach

It is important to determine whether the persistent cognitive and fatigue complaints, as part of post-acute sequelae of COVID-19 (PASC), are associated with underlying patterns and specific symptoms clusters. Therefore, the aim of the present study was to investigate symptom clus...

Sex work or male-with-male sexual activity and the risks of HIV and hepatitis C acquisition among people who inject drugs: a global systematic review and meta-analysis

Background People who inject drugs (PWID) may engage in sexual behaviours that increase their HIV and hepatitis C virus (HCV) risk, including sex work and male-with-male sexual activity. We undertook a global systematic review to assess whether PWID who engage in these behaviours...

Towards a suitable biomarker for childhood screening for familial hypercholesterolemia: a systematic literature review

Familial hypercholesterolemia (FH) is a common genetic disorder causing elevated low-density lipoprotein cholesterol (LDL-c) concentrations from birth, resulting in a high risk of premature cardiovascular disease. Despite effective early treatment, FH remains underdiagnosed in ch...

Geographic variation in migration background and SARS-CoV-2 vaccination uptake in the Madrid region, Spain: an ecological analysis

Abstract Background People with a migration background have experienced a high burden of SARS-CoV-2 infection and severe disease progression. Promoting vaccination uptake among these groups is crucial, however, in many areas, uptake has remained unevaluated. This study explored t...

Occupational nanoparticle exposure and its effects on pulmonary health, cardiovascular health, and systemic biomarkers: a scoping review

Abstract Background Occupational exposure to nanoparticles occurs across diverse industrial sectors. Preclinical studies indicate that such exposures may pose health risks. However, characterization of these risks in real-world occupational-environments remains limited. Objective...

Exploring the transcriptional crosstalk between adipose tissue and locoregional recurrence in breast cancer using independent component analysis

Locoregional recurrence (LRR) poses a persistent clinical challenge in breast cancer, with emerging evidence implicating the tumor-associated adipose tissue in modulating recurrence risk. This study investigates shared transcriptional programs between adipose tissue and breast tu...

The effect of proximity of COVID-19 test facilities on test uptake: two quasi-experimental trials

Access to testing sites is a critical component in reducing the spread of a virus during infectious disease outbreaks. For example, distance to the testing site has been mentioned as an important self-reported barrier for test uptake during the COVID-19 pandemic. Despite its impo...

Unpacking pension-climate governance: the finance-climate governance nexus and its implications for pension fund climate action and fossil fuel phaseout

Abstract Through the Paris Agreement’s commitment to making financial flows consistent with emissions reduction pathways, large institutional investors, including pension funds, have been implicitly conscripted into efforts to leave fossil fuels underground. Yet despite the atten...