German Climate Computing Centre

Automated Production of Gene-Edited CAR-T Cells for People Living with HIV

Adoptive transfer of gene-modified autologous T cells, for example, expressing chimeric antigen receptors (CARs), is a promising therapy option for a variety of malignant and nonmalignant diseases. Given their increased risk to develop certain cancer types, namely lymphoma, and t...

Variability of internal snow properties over Antarctic late summer sea ice on different spatial scales

Snow on Antarctic sea ice strongly affects thermodynamic processes, sea ice mass balance, and microwave remote sensing, yet its spatial variability and characteristic length scales remain poorly quantified. The aim of this study is to provide a spatially extensive, layer-resolved...

A Survey and Comparison of Ocean Biogeochemistry Models in the natESM Initiative

This paper presents a comprehensive survey of contemporary ocean biogeochemistry (OBGC) models within the natESM (National Earth System Modeling) initiative, conducted by the natESM Ocean Biogeochemistry Working Group. We systematically document nine OBGC models spanning diverse...

The Climate Model Output Rewriter (CMOR)

Features User input files can now override the source, experiment, and institution global-attribute values when those attributes are not required by the controlled vocabulary. (#988, #995) Added CMIP7 site dimension examples for Python, Fortran, and C, including their generated N...

Volcano–climate interactions: reframing the volcano–climate puzzle

Explosive volcanic eruptions are major natural perturbations of the Earth system. By increasing stratospheric aerosol loading, they exert a dual radiative forcing: enhanced scattering of incoming solar radiation induces global surface cooling, while absorption of terrestrial radi...