Georg Speyer Haus

Effects of urban building structures on the distribution of breeding sites and ovitrap egg counts of Aedes albopictus in Pfaffengrund, Heidelberg, Germany

Abstract Background In recent years, the increased abundance and expansion of the invasive species Aedes albopictus has become a nuisance and health threat in urban areas of Germany. While intensive control and monitoring measures have shown promising results to reduce population...

Sleep duration links to biological aging clocks: when sleep gets tough, aging gets going

In a recent large-scale study of biological ageing clocks published in Nature , the MULTI Consortium now shows sleep, often treated as a lifestyle habit, is a measurable sign of temporal biology. Their work suggests that deviations from optimal sleep duration are associated with...

Oncofetal cell states: cell plasticity drives invasion in premetastatic colorectal tumors

In a recent publication in Nature , Buissant des Amorie et al. provide evidence that an oncofetal cell state which is associated with advanced disease, chemoresistance and metastatic competence emerges already in early-stage T1 colorectal cancer (CRC). Intriguingly, oncofetal cel...

Accelerating Translation of NK Cell Therapies to the Clinic: A European Perspective

Adoptive immunotherapies have emerged as a promising strategy in the treatment of hematological malignancies. To date, seven chimeric antigen receptor (CAR)-T cell products have obtained market authorization in Europe for B-cell malignancies, where they have revolutionized treatm...