Genesis Medical Center

AEON Drive: Systems Architecture for Candidate Field Coupling, Geodesic-Riding Dynamics, and Experimental Tests

The AEON Drive is an exploratory and falsifiable research framework asking whether a controlled, coherent electromagnetic field architecture could produce any reproducible interaction beyond ordinary electromagnetic momentum transfer and the extremely small spacetime curvature pr...

Co-Folding Confidence Dispersion Is a Coarse Binder Filter, Not an Affinity Ranker: Boltz-2 sigma-iptm Evaluated Against Potency Rank, Same-Chemotype Weak Binders, and Property-Matched Decoys on Matrix Metalloproteinase-1

The dispersion of co-folding confidence across an inference ensemble is widely used to triage protein-ligand predictions, but what it measures has not been fixed against experiment. This work evaluates Boltz-2 sigma-iptm, the standard deviation of iptm over 100 diffusion samples,...

AEON Drive: Systems Architecture for Candidate Field Coupling, Geodesic-Riding Dynamics, and Experimental Tests

The AEON Drive is an exploratory and falsifiable research framework asking whether a controlled, coherent electromagnetic field architecture could produce any reproducible interaction beyond ordinary electromagnetic momentum transfer and the extremely small spacetime curvature pr...

Co-Folding Confidence Dispersion Is a Coarse Binder Filter, Not an Affinity Ranker: Boltz-2 sigma-iptm Evaluated Against Potency Rank, Same-Chemotype Weak Binders, and Property-Matched Decoys on Matrix Metalloproteinase-1

The dispersion of co-folding confidence across an inference ensemble is widely used to triage protein-ligand predictions, but what it measures has not been fixed against experiment. This work evaluates Boltz-2 sigma-iptm, the standard deviation of iptm over 100 diffusion samples,...