Institution
General University Hospital of Patras
Recent research
- BiologyOpen access
Regulated Cell Death in Reproductive Biology: Mechanisms and Therapeutic Opportunities
Regulated cell death (RCD) has emerged as a fundamental determinant of cellular homeostasis and tissue remodeling, extending far beyond the classical concept of apoptosis. The identification of emerging RCD pathways, including ferroptosis, pyroptosis, necroptosis, cuproptosis, PA...
- Health & Medicine
Black Pleural Effusion as a Rare Presentation of Serotype 3 Pneumococcal Empyema
Black pleural effusion (BPE) is exceptionally rare in children, with only 1 previously reported pediatric case linked to a pancreaticopleural fistula, while adult cases are typically associated with rupture of pancreatic pseudocysts, malignancy, fungal infection, or hemorrhage. A...
- Health & MedicineOpen access
ELN vs. IPSS-M in MDS/AML: Which Prognostic System Should Guide Clinical Decision-Making?
The recognition of myelodysplastic syndrome/acute myeloid leukemia (MDS/AML) as a distinct overlap entity by the International Consensus Classification (ICC) has introduced new challenges in prognostication and therapeutic decision-making. Defined by 10–19% blasts in the absence...
- Health & MedicineOpen access
Background/Objectives: The optimal surgical approach for Percutaneous KyphoPlasty (PKP) in patients with recent single-level Osteoporotic Vertebral Compression Fractures (OVCFs) remains controversial. Most available previous meta-analyses included studies with variable heterogene...
- Health & MedicineOpen access
Resectability in pancreatic ductal adenocarcinoma (PDAC) has traditionally been defined according to tumor–vessel relationship on cross-sectional imaging. However, anatomical criteria alone fail to identify occult systemic disease and do not reliably predict early postoperative r...
- Health & MedicineOpen access
INTRODUCTION: The randomised SIRONA trial showed that sirolimus-coated balloon (SCB) angioplasty was non-inferior to paclitaxel-coated balloon angioplasty (PCB) regarding femoropopliteal primary patency. There was no difference in clinically driven target lesion revascularisation...
- Health & MedicineOpen access
Background/Objectives: Sciatica and hip osteoarthritis (OA) are common causes of lower extremity pain and functional impairment. Because both conditions may produce overlapping symptoms, distinguishing them can be challenging. Misdiagnosis may lead to inappropriate treatment, del...