General Electric (Spain)

Predicting [177Lu]Lu-PSMA-617 SPECT/CT-based absorbed dose to whole-body tumor volume from pre-therapy [68Ga]Ga-PSMA-11 PET metrics and common blood biomarkers

It has been shown that absorbed dose (AD) to whole-body tumor volume (WBTV) from [ 177 Lu]Lu-PSMA-617 radiopharmaceutical therapy (RPT) correlates with treatment response. Pre-therapy estimation of AD to WBTV could therefore aid clinicians with patient selection and dosimetry-gui...

Comparison of Continuous‐Time Random Walk and Fractional Order Calculus Diffusion Models for Preoperative Breast Lesion Characterization: Diagnosis, Biomarker Prediction and Molecular Subtyping

BACKGROUND: Accurate preoperative characterization of breast lesions is important for individualized management. The conventional monoexponential (Mono) model has limited ability to capture the complex microstructure of lesions. Non-Gaussian diffusion models, including continuous...

Mean apparent propagator MRI of distributed brain microstructure in anxiety-related heterogeneity among children with autism spectrum disorder: associations with thyroid hormones and trace elements

Anxiety-related symptoms contribute substantially to clinical variability in autism spectrum disorder (ASD), but the extent to which peripheral endocrine and trace-element measures map onto brain microstructure remains insufficiently defined. We investigated whether thyroid-relat...

Non‐inferiority analysis of a fetal heart rate artificial intelligence algorithm to registered nurse assessment

Abstract Introduction Cardiotocography (CTG) is widely used for monitoring fetal heart rate (FHR) and uterine activity (UA) during pregnancy and labor. Clinician interpretation of CTG tracings may be subjective, leading to significant inter‐ and intra‐observer variability and inc...

Quantitative Evaluation of Cervical Spine Morphometry: Zero Echo Time MRI Versus Multislice CT

BACKGROUND: For preoperative cervical assessment, both CT and MRI are often required for bony and soft-tissue evaluation, yet CT entails radiation and MRI poorly depicts cortical bone. ZTE offers CT-like contrast in one examination, but whether it correlates with CT for quantitat...

Arterial Spin‐Labeling MRI at the Cortical‐ CSF Interface: A Novel Biomarker in Alzheimer Disease

BACKGROUND/OBJECTIVE: Arterial spin-labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF-adjacent water transport physiology. We developed an automated pipeline to extract cortical-CSF interface (IF) perfusion for compar...