Gelre Hospitals

Dupilumab in Pediatric Eosinophilic Esophagitis

BACKGROUND AND OBJECTIVES: Dupilumab is an approved biologic therapy for eosinophilic esophagitis (EoE); however, real-world pediatric data remain limited. The aim of this study is to evaluate the effectiveness and safety of dupilumab in children with EoE enrolled in the internat...

Acetic acid chromoendoscopy for detection of neoplastic Barrett’s oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial)

Abstract Objective To assess the added value of acetic acid chromoendoscopy (AAC) for the detection of dysplasia and oesophageal adenocarcinoma during Barrett’s oesophagus surveillance endoscopies. Design Prospective, open label, stepped wedge cluster, randomised trial. Setting 1...