Gandhi Medical College & Hospital

MIRA: A Multi-Stage Triage Pipeline with a Triage-Stage Red-Flag Layer, Designed for WhatsApp-Based Use in Low-Resource, Multilingual Settings — An Interim Evaluation on a 30-Case Synthetic Set

MIRA is a research prototype of a fixed six-stage sequential triage pipeline (five LLM-backed agents plus a deterministic red-flag layer at the Triage stage) for WhatsApp-style symptom messages in English and romanized Hindi/Telugu. This corrected version supersedes v1.2-interim,...

MIRA: A WhatsApp-Deployed, Rule-Overridden Multi-Agent Pipeline for Pre-Contact Clinical Triage in Low-Resource, Multilingual Settings

MIRA is a five-node pipeline (Intake → Language → Diagnostic → Triage → Referral) that accepts a WhatsApp message describing symptoms, in the patient's own language including romanized Hindi and Telugu, and returns a triage decision (Emergency / Urgent / Routine) plus a referral....

Comparison of short-term outcomes in thalassemia major ABO mismatch versus ABO compatible in allogeneic hematopoietic stem cell transplant

Objective: Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment for thalassemia major. ABO incompatibility between donor and recipient is common, but its clinical significance remains uncertain. The objective of the study is to assess the impac...

[ 177 Lu]Lu‐PSMA‐617 Plus Short‐Course Priming With Enzalutamide in Metastatic Castration‐Resistant Prostate Cancer: A Single‐Arm Phase 2 Trial (Lu‐PRIME)

ABSTRACT Background [ 177 Lu]Lu‐PSMA‐617 has been an approved treatment modality for metastatic castration‐resistant prostate cancer (mCRPC). Recent studies have shown PSMA upregulation following enzalutamide, which may enhance the outcomes with [ 177 Lu]Lu‐PSMA‐617. This study a...

Mitophagy and Noncoding RNA Regulation in Type 2 Diabetes Mellitus: Molecular Mechanisms, Tissue-Specific Evidence and Translational Perspective

Despite significant therapeutic advances, T2DM remains a global public health challenge that leads to multiple complications, including cardiovascular, renal, hepatic, and neurodegenerative disorders. Mitochondrial dysfunction and impaired mitophagy remain fundamental, yet incomp...

Diffuse Long-segment Colonic Wall Thickening Mimicking Abdominal Tuberculosis: A Diagnostic Challenge Revealing Signet Ring Cell Carcinoma in a 24-year-old Male

ABSTRACT: Long-segment bowel wall thickening with ascites and omental involvement is usually attributed to abdominal tuberculosis, particularly in areas endemic to tuberculosis. However, certain cancers, like diffuse infiltrative colorectal carcinomas, can mimic the imaging findi...