Galicia Sur Biomedical Foundation

Health utilities in individuals with alpha-1 antitrypsin deficiency with and without COPD from the EARCO registry

Background Data on health utilities in Alpha-1 antitrypsin deficiency (AATD) are scarce. This study aimed to evaluate health-related quality of life (HRQoL) using the EQ-5D in a cohort of AATD Pi*ZZ individuals from the European AATD Research Collaboration (EARCO) registry and to...

CLDN18 as a novel junctional biomarker enhancing multi-gene classification of pancreatic cancer

Pancreatic adenocarcinoma (PAAD) remains one of the most lethal cancers, largely due to the lack of reliable diagnostic biomarkers. Through integrative transcriptomic and proteomic analyses, we evaluated a four-gene signature comprising CLDN18, CEACAM5, FUT3, and FUT6, capable of...

Lifestyle and its relationship with health literacy, sense of coherence and sociodemographic factors in a Spanish primary care population: a multicenter cross-sectional study

Health behaviors are driven by a complex interplay of individual and structural factors. While health literacy and sense of coherence are widely studied as psychosocial enablers of healthy lifestyles, evidence comparing their impact against broader social determinants of health r...

Ensuring pragmatic and equitable paths forward for hepatitis B virus infection eradication in Latin America

INTRODUCTION: Latin America occupies a paradoxical position in hepatitis B virus (HBV) elimination: aggregate prevalence is low, yet the region remains far from the WHO and PAHO 2030 targets because the burden is structurally concealed within underserved populations and fragmente...

Musculoskeletal Pain and Satisfaction with an Injury-Prevention Workshop Among Young String and Wind Musicians: An Observational Study

Background/Objectives: Musculoskeletal injuries are highly prevalent among musicians, with the neck and shoulders being the most frequently reported areas of pain. Preventive education should be included to help understand and avoid health risks associated with musical performanc...

Criterion A in developmental coordination disorder: Is motor competence efficiently assessed? A systematic review and meta-analysis of mixed evidence from standardized assessments

Background Standardized motor batteries are widely used to assess motor competence in children with developmental coordination disorder (DCD), although it remains unclear whether they consistently capture the domains most affected by the disorder . Aims This systematic review and...

The Impact of ICT on the Independent Living of Adolescents in Residential Child Protection Care

ABSTRACT In an increasingly digitalized social context, digital competences have become a fundamental resource for social participation, access to opportunities and independent living. Accordingly, this study examines the impact of digital competence on the lives of young people...