G H Raisoni University

LPR-1-Mediated targeted intranasal delivery of lentinan-loaded polymeric nanocarriers for GBM therapy via modulation of apoptotic signalling

Aim To develop and evaluate a lactoferrin (Lf)-functionalized polyethylene glycol (PEG)-grafted chitosan (CS) nanocarriers (NCs) for low-density lipoprotein receptor-related protein-1 (LRP1)-mediated intranasal delivery of lentinan (LNT) to enhance brain targeting and anti-gliobl...