Future University in Egypt

Semaglutide and Tirzepatide Suppress Hepatic Fatty Acid Uptake and Fatty Acid β-Oxidation in High-Fat Diet-Induced Obesity Mice

Abstract Glucagon-like peptide-1 (GLP-1) and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists show high efficacy in treating obesity and metabolic dysfunction-associated liver diseases, conditions that collectively represent one of the most challeng...

Enhanced odontoblast regeneration and anti-inflammatory effects of nanocurcumin-loaded BM-MSC-derived exosomes in an LPS-induced periodontitis rat model

Abstract Background Periodontitis is commonly known as a chronic inflammatory disease which adversely affects pulpal and periodontal tissues, including odontoblasts. Bone marrow mesenchymal stem cell-derived exosomes (BM-MSC-Exo) and nanocurcumin (NCUR) possess anti-inflammatory...

Shear capacity of tapered web panel of plate girders with web opening

Abstract Tapered plate girders with web openings are widely used to route services and reduce weight, yet current provisions only partly capture the combined effects of tapering angle, opening size, panel aspect ratio, and web slenderness. A total of 115 shell finite-element (FE)...

A Survey of Causal Learning in Graph-Based Recommender Systems

Graph-based recommender systems (GBRs) have achieved remarkable success by leveraging Graph Neural Networks (GNNs) to model complex user-item interactions and structural relationships. However, they still face major challenges in real-world environments, including out-of-distribu...

A machine learning approach to predict treatment response in myofascial pain patients receiving masseter trigger point injections

BACKGROUND: Trigger point injection (TPI) therapy is widely used for masseter myofascial pain syndrome (MPS), yet outcomes vary substantially. Individualized prediction tools are lacking, often leading to trial-and-error treatment selection. OBJECTIVE: To develop, externally vali...