Fundação Carlos Chagas

Molecular remodelling of Cryptococcus neoformans during adaptation to host temperature

Introduction. The ability of Cryptococcus neoformans to adapt to host temperature is an important feature of its pathogenic potential and requires extensive cellular remodelling. Hypothesis/Gap Statement. Although C. neoformans undergoes substantial molecular changes at host temp...

Oncoplastic Reconstruction of the Anterior Chest Wall Using a Latissimus Dorsi Myocutaneous Flap: A Case Report

Background: Dermatofibrosarcoma protuberans (DFSP) is an uncommon cutaneous fibroblastic neoplasm characterized by infiltrative growth, low metastatic potential, and a high risk of local recurrence following incomplete excision. Large or recurrent tumors of the anterior chest wal...

Individual and Combined Effects of Commercial Glyphosate and Dicamba-Based Herbicide Formulations on Cytotoxicity, Oxidative Stress and Cell Death on Human Intestinal Caco-2 Cells

Pesticide contamination of food and environmental matrices represents a potential risk to human health. This study investigated the toxicological effects of commercial glyphosate and dicamba-based herbicide formulations, individually and in combination, on human intestinal epithe...

Reporting Gaps in Human Medicinal Mushroom Studies: Implications for Interpretation, Formulation, and Real-World Use

Human studies on medicinal mushrooms are increasingly cited in scientific, clinical, and commercial discussions, yet interpretation is often weakened by incomplete reporting of the tested intervention material. This work examined published human studies on Lion’s Mane (Hericium e...

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins

ABSTRACT Background Chagas disease (CD) is caused by Trypanosoma cruzi Chagas (genus Trypanosoma , family Trypanosomatidae, order Kinetoplastida), that is widespread in Latin America. The main hosts are humans and other domestic mammals, including dogs and cats. Studies have iden...