Fundação Bahiana de Infectologia

Development of a Single Thermal Cycling Multiplex RT-qPCR Assay for Rapid Arbovirus Detection

Background: The co-circulation of multiple arboviruses with similar clinical presentations poses a significant challenge for public health surveillance. This study aimed to develop and clinically validate a novel multiplex RT-qPCR assay for the simultaneous detection of five arbo...

Do Preoperative Glucagon-Like Peptide-1 Receptor Agonists Influence Lumbar Fusion Outcomes? A Systematic Review and Meta-Analysis

Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are increasingly used in patients with obesity and type 2 diabetes, but lumbar fusion-specific associations with postoperative outcomes remain uncertain. Objective To evaluate the association between preoperative GLP...

Classification of Monads and a New Moduli Component of Stable Rank 2 Bundles on $$\mathbb {P}^3$$ with Even Determinant and $$c_2=9$$

Abstract The goal of this paper is to classify all minimal monads whose cohomology is a stable rank 2 bundle on $$\mathbb {P}^3$$ P 3 with Chern classes $$c_1=0$$ c 1 = 0 and $$c_2=9$$ c 2 = 9 , with the possible exception of two non-negative minimal monads. This extends the clas...

Woven endobridge device compared to stent-assisted coiling and microsurgical clipping for intracranial aneurysms

Background: Endovascular techniques and devices, including Woven EndoBridge (WEB) and stent-assisted coiling (SAC), expand the choice of therapies for complex aneurysms, while the evidence directly comparing them to microsurgical clipping (MSC) remains very limited. This meta-ana...

Obinutuzumab Induces Histological Remission and Deep Kidney Parenchymal B-Cell Depletion in Patients with Lupus Nephritis: Exploratory Analyses of the Phase III REGENCY Trial

Objectives The REGENCY trial ( NCT04221477 ) demonstrated superiority of obinutuzumab (OBI) plus standard therapy (+ST) vs placebo (PBO) +ST in achieving complete renal response (CRR) at Week 76 (W76) in adults with active lupus nephritis (LN). These exploratory analyses aimed to...