Functional Genomics Center Zurich

A preconceptional stress model identifies thalamostriatal substrates of intergenerational vulnerability

Abstract Antenatal depression affects up to 20% of pregnancies worldwide and is associated with increased neuropsychiatric vulnerability in offspring, yet the enduring behavioural, neuroanatomical, and molecular features associated with maternal mood disturbance remain incomplete...

The mosquito-stage transcriptome of the neglected malaria parasite Plasmodium malariae reveals species-specific gene expression signatures and functional adaptations

ABSTRACT To survive and multiply in different host niches, malaria parasites require sets of proteins that are expressed during the life cycle in a timely manner. Plasmodium malariae is a human malaria parasite that is present in most malaria-endemic regions. However, this specie...